Aliskiren Hemifumarate Proliposomes for Improved Oral Drug Delivery: Formulation Development, In Vitro and In Vivo Permeability Testing

The objective of this study was to develop proliposomal formulations for a poorly bioavailable drug, aliskiren hemifumarate (AKH). A solvent evaporation method was used to prepare proliposomes using different lipids. The lipids of selection were soy phosphatidylcholine (SPC), dimyristoylphosphatidyl...

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Detalles Bibliográficos
Autores principales: Kunamaneni, Priyanka, Kovvasu, Surya, Yeung, Steven, Wang, Jeffrey, Shah, Salim, Betageri, Guru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369865/
https://www.ncbi.nlm.nih.gov/pubmed/35956779
http://dx.doi.org/10.3390/molecules27154828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369865/
https://www.ncbi.nlm.nih.gov/pubmed/35956779
http://dx.doi.org/10.3390/molecules27154828

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