Molecular Basis of Inhibitory Mechanism of Naltrexone and Its Metabolites through Structural and Energetic Analyses

Naltrexone is a potent opioid antagonist with good blood–brain barrier permeability, targeting different endogenous opioid receptors, particularly the mu-opioid receptor (MOR). Therefore, it represents a promising candidate for drug development against drug addiction. However, the details of the mol...

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Detalles Bibliográficos
Autor principal: Bello, Martiniano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369988/
https://www.ncbi.nlm.nih.gov/pubmed/35956868
http://dx.doi.org/10.3390/molecules27154919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369988/
https://www.ncbi.nlm.nih.gov/pubmed/35956868
http://dx.doi.org/10.3390/molecules27154919

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