Biochemical Evolution of a Potent Target of Mosquito Larvicide, 3-Hydroxykynurenine Transaminase

A specific mosquito enzyme, 3-hydroxykynurenine transaminase (HKT), is involved in the processing of toxic metabolic intermediates of the tryptophan metabolic pathway. The HKT enzymatic product, xanthurenic acid, is required for Plasmodium spp. development in the mosquito vectors. Therefore, an inhi...

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Detalles Bibliográficos
Autores principales: Chen, Huaqing, Bhowmick, Biswajit, Tang, Yu, Lozano-Fernandez, Jesus, Han, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369995/
https://www.ncbi.nlm.nih.gov/pubmed/35956879
http://dx.doi.org/10.3390/molecules27154929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369995/
https://www.ncbi.nlm.nih.gov/pubmed/35956879
http://dx.doi.org/10.3390/molecules27154929

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