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Biochemical Evolution of a Potent Target of Mosquito Larvicide, 3-Hydroxykynurenine Transaminase
A specific mosquito enzyme, 3-hydroxykynurenine transaminase (HKT), is involved in the processing of toxic metabolic intermediates of the tryptophan metabolic pathway. The HKT enzymatic product, xanthurenic acid, is required for Plasmodium spp. development in the mosquito vectors. Therefore, an inhi...
Autores principales: | Chen, Huaqing, Bhowmick, Biswajit, Tang, Yu, Lozano-Fernandez, Jesus, Han, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369995/ https://www.ncbi.nlm.nih.gov/pubmed/35956879 http://dx.doi.org/10.3390/molecules27154929 |
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