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Identification of 3-Oxindole Derivatives as Small Molecule HIV-1 Inhibitors Targeting Tat-Mediated Viral Transcription

The heterocyclic indole structure has been shown to be one of the most promising scaffolds, offering various medicinal advantages from its wide range of biological activity. Nonetheless, the significance of 3-oxindole has been less known. In this study, a series of novel 3-oxindole-2-carboxylates we...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Eun, Shin, Young Hyun, Cho, Jung-Eun, Myung, Subeen, Kim, Hong Gi, Kim, Kyung-Chang, Park, Chul Min, Yoon, Cheol-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370035/
https://www.ncbi.nlm.nih.gov/pubmed/35956872
http://dx.doi.org/10.3390/molecules27154921