Exploration of Spirocyclic Derivatives of Ciprofloxacin as Antibacterial Agents

The previously reported as well as newly synthesized derivatives of the 1-oxa-9-azaspiro[5.5]undecane were employed in the synthesis of thirty-six derivatives of ciprofloxacin using commercially available 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid and the literature...

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Detalles Bibliográficos
Autores principales: Lukin, Alexei, Chudinov, Mikhail, Vedekhina, Tatiana, Rogacheva, Elizaveta, Kraeva, Lyudmila, Bakulina, Olga, Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370040/
https://www.ncbi.nlm.nih.gov/pubmed/35956812
http://dx.doi.org/10.3390/molecules27154864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370040/
https://www.ncbi.nlm.nih.gov/pubmed/35956812
http://dx.doi.org/10.3390/molecules27154864

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