Stability and Existence of Noncanonical I-motif DNA Structures in Computer Simulations Based on Atomistic and Coarse-Grained Force Fields

Cytosine-rich DNA sequences are able to fold into noncanonical structures, in which semi-protonated cytosine pairs develop extra hydrogen bonds, and these bonds are responsible for the overall stability of a structure called the i-motif. The i-motif can be formed in many regions of the genome, but t...

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Detalles Bibliográficos
Autores principales: Panczyk, Tomasz, Nieszporek, Krzysztof, Wolski, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370271/
https://www.ncbi.nlm.nih.gov/pubmed/35956863
http://dx.doi.org/10.3390/molecules27154915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370271/
https://www.ncbi.nlm.nih.gov/pubmed/35956863
http://dx.doi.org/10.3390/molecules27154915

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