Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytostatic Drugs In Vitro

Isatis tinctoria and its indigo dyes have already provided highly active anti-leukaemic lead compounds, with the focus mainly being on indirubin, whereas indigo itself is inactive. There are many more indigoids to find in this plant extract, for example, quingdainone, an indigoid derived from trypta...

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Detalles Bibliográficos
Autores principales: Baas, Jennifer, Bieringer, Sebastian, Frias, Corazon, Frias, Jerico, Soehnchen, Carolina, Urmann, Corinna, Ritter, Steffi, Riepl, Herbert, Prokop, Aram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370279/
https://www.ncbi.nlm.nih.gov/pubmed/35956988
http://dx.doi.org/10.3390/molecules27155038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370279/
https://www.ncbi.nlm.nih.gov/pubmed/35956988
http://dx.doi.org/10.3390/molecules27155038

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