Identification of Estradiol Benzoate as an Inhibitor of HBx Using Inducible Stably Transfected HepG2 Cells Expressing HiBiT Tagged HBx

HBx plays a significant role in the cccDNA epigenetic modification regulating the hepatitis B virus (HBV) life cycle and in hepatocyte proliferation and carcinogenesis. By using the sleeping-beauty transposon system, we constructed a tetracycline-induced HBx-expressing stable cell line, SBHX21. HBx...

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Detalles Bibliográficos
Autores principales: He, Jingjing, Wu, Jingwen, Chen, Jingwen, Zhang, Shenyan, Guo, Yifei, Zhang, Xueyun, Han, Jiajia, Zhang, Yao, Guo, Yue, Lin, Yanxue, Yu, Weien, Kong, Yide, Shen, Zhongliang, Mao, Richeng, Zhang, Jiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370419/
https://www.ncbi.nlm.nih.gov/pubmed/35956950
http://dx.doi.org/10.3390/molecules27155000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370419/
https://www.ncbi.nlm.nih.gov/pubmed/35956950
http://dx.doi.org/10.3390/molecules27155000

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