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An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022

Since the early 1980s, phosphodiesterase 4 (PDE4) has been an attractive target for the treatment of inflammation-based diseases. Several scientific advancements, by both academia and pharmaceutical companies, have enabled the identification of many synthetic ligands for this target, along with the...

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Detalles Bibliográficos
Autores principales: Crocetti, Letizia, Floresta, Giuseppe, Cilibrizzi, Agostino, Giovannoni, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370432/
https://www.ncbi.nlm.nih.gov/pubmed/35956914
http://dx.doi.org/10.3390/molecules27154964