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Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation

This work is one of our efforts to discover potent anticancer agents. We modified the most promising derivative of our previous work concerned with the development of VEGFR-2 inhibitor candidates. Thirteen new compounds based on benzoxazole moiety were synthesized and evaluated against three human c...

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Detalles Bibliográficos
Autores principales: Elwan, Alaa, Abdallah, Abdallah E., Mahdy, Hazem A., Dahab, Mohammed A., Taghour, Mohammed S., Elkaeed, Eslam B., Mehany, Ahmed B. M., Nabeeh, Ahmed, Adel, Mohammed, Alsfouk, Aisha A., Elkady, Hazem, Eissa, Ibrahim H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370530/
https://www.ncbi.nlm.nih.gov/pubmed/35956997
http://dx.doi.org/10.3390/molecules27155047