Targeting Glutaminase by Natural Compounds: Structure-Based Virtual Screening and Molecular Dynamics Simulation Approach to Suppress Cancer Progression

Cancer cells change their glucose and glutamine (GLU) metabolism to obtain the energy required to continue growing. Glutaminase (GLS) plays a crucial role in promoting cell metabolism for cancer cell growth; targeting GLU metabolism by inhibiting GLS has attracted interest as a potential cancer mana...

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Detalles Bibliográficos
Autores principales: Tabrez, Shams, Zughaibi, Torki A., Hoque, Mehboob, Suhail, Mohd, Khan, Mohammad Imran, Khan, Azhar U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370672/
https://www.ncbi.nlm.nih.gov/pubmed/35956989
http://dx.doi.org/10.3390/molecules27155042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370672/
https://www.ncbi.nlm.nih.gov/pubmed/35956989
http://dx.doi.org/10.3390/molecules27155042

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