Why Ortho- and Para-Hydroxy Metabolites Can Scavenge Free Radicals That the Parent Atorvastatin Cannot? Important Pharmacologic Insight from Quantum Chemistry

The pharmaceutical success of atorvastatin (ATV), a widely employed drug against the “bad” cholesterol (LDL) and cardiovascular diseases, traces back to its ability to scavenge free radicals. Unfortunately, information on its antioxidant properties is missing or unreliable. Here, we report detailed...

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Detalles Bibliográficos
Autor principal: Bâldea, Ioan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370721/
https://www.ncbi.nlm.nih.gov/pubmed/35956986
http://dx.doi.org/10.3390/molecules27155036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370721/
https://www.ncbi.nlm.nih.gov/pubmed/35956986
http://dx.doi.org/10.3390/molecules27155036

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