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KSHV RTA antagonizes SMC5/6 complex-induced viral chromatin compaction by hijacking the ubiquitin-proteasome system

Kaposi’s sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA virus with the capacity to establish life-long latent infection. During latent infection, the viral genome persists as a circular episome that associates with cellular histones and exists as a nonintegrated minichromosome in the...

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Detalles Bibliográficos
Autores principales: Han, Chunyan, Zhang, Dun, Gui, Chenwu, Huang, Liang, Chang, Sijia, Dong, Lianghui, Bai, Lei, Wu, Shuwen, Lan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371351/
https://www.ncbi.nlm.nih.gov/pubmed/35914008
http://dx.doi.org/10.1371/journal.ppat.1010744