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Full spectrum flow cytometry reveals mesenchymal heterogeneity in first trimester placentae and phenotypic convergence in culture, providing insight into the origins of placental mesenchymal stromal cells

Single-cell technologies (RNA-sequencing, flow cytometry) are critical tools to reveal how cell heterogeneity impacts developmental pathways. The placenta is a fetal exchange organ, containing a heterogeneous mix of mesenchymal cells (fibroblasts, myofibroblasts, perivascular, and progenitor cells)....

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Detalles Bibliográficos
Autores principales: Boss, Anna Leabourn, Damani, Tanvi, Wickman, Tayla J, Chamley, Larry W, James, Joanna L, Brooks, Anna ES
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371602/
https://www.ncbi.nlm.nih.gov/pubmed/35920626
http://dx.doi.org/10.7554/eLife.76622