The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages

Dysregulated neutrophilic inflammation can be highly destructive in chronic inflammatory diseases due to prolonged neutrophil lifespan and continual release of histotoxic mediators in inflamed tissues. Therapeutic induction of neutrophil apoptosis, an immunologically silent form of cell death, may b...

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Detalles Bibliográficos
Autores principales: Herman, Kimberly D., Wright, Carl G., Marriott, Helen M., McCaughran, Sam C., Bowden, Kieran A., Collins, Mark O., Renshaw, Stephen A., Prince, Lynne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371615/
https://www.ncbi.nlm.nih.gov/pubmed/35967296
http://dx.doi.org/10.3389/fimmu.2022.956991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371615/
https://www.ncbi.nlm.nih.gov/pubmed/35967296
http://dx.doi.org/10.3389/fimmu.2022.956991

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