Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating

Thermoregulation is an important aspect of human homeostasis, and high temperatures pose serious stresses for the body. Malignant hyperthermia (MH) is a life-threatening disorder in which body temperature can rise to a lethal level. Here we employ an optically controlled local heat-pulse method to m...

Descripción completa

Detalles Bibliográficos
Autores principales: Oyama, Kotaro, Zeeb, Vadim, Yamazawa, Toshiko, Kurebayashi, Nagomi, Kobirumaki-Shimozawa, Fuyu, Murayama, Takashi, Oyamada, Hideto, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U., Nishino, Ichizo, Harada, Yoshie, Fukuda, Norio, Ishiwata, Shin’ichi, Suzuki, Madoka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371657/
https://www.ncbi.nlm.nih.gov/pubmed/35925888
http://dx.doi.org/10.1073/pnas.2201286119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371657/
https://www.ncbi.nlm.nih.gov/pubmed/35925888
http://dx.doi.org/10.1073/pnas.2201286119

Ejemplares similares