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Fic-mediated AMPylation tempers the unfolded protein response during physiological stress

The proper balance of synthesis, folding, modification, and degradation of proteins, also known as protein homeostasis, is vital to cellular health and function. The unfolded protein response (UPR) is activated when the mechanisms maintaining protein homeostasis in the endoplasmic reticulum become o...

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Detalles Bibliográficos
Autores principales: Casey, Amanda K., Gray, Hillery F., Chimalapati, Suneeta, Hernandez, Genaro, Moehlman, Andrew T., Stewart, Nathan, Fields, Hazel A., Gulen, Burak, Servage, Kelly A., Stefanius, Karoliina, Blevins, Aubrie, Evers, Bret M., Krämer, Helmut, Orth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371680/
https://www.ncbi.nlm.nih.gov/pubmed/35914137
http://dx.doi.org/10.1073/pnas.2208317119