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Fic-mediated AMPylation tempers the unfolded protein response during physiological stress
The proper balance of synthesis, folding, modification, and degradation of proteins, also known as protein homeostasis, is vital to cellular health and function. The unfolded protein response (UPR) is activated when the mechanisms maintaining protein homeostasis in the endoplasmic reticulum become o...
Autores principales: | Casey, Amanda K., Gray, Hillery F., Chimalapati, Suneeta, Hernandez, Genaro, Moehlman, Andrew T., Stewart, Nathan, Fields, Hazel A., Gulen, Burak, Servage, Kelly A., Stefanius, Karoliina, Blevins, Aubrie, Evers, Bret M., Krämer, Helmut, Orth, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371680/ https://www.ncbi.nlm.nih.gov/pubmed/35914137 http://dx.doi.org/10.1073/pnas.2208317119 |
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