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Gammaherpesvirus-mediated repression reveals EWSR1 to be a negative regulator of B cell responses

The germinal center (GC) plays a central role in the generation of antigen-specific B cells and antibodies. Tight regulation of the GC is essential due to the inherent risks of tumorigenesis and autoimmunity posed by inappropriate GC B cell processes. Gammaherpesviruses such as Epstein–Barr virus (E...

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Detalles Bibliográficos
Autores principales: Wang, Yiping, Feswick, April, Apostolou, Vasiliki, Petkov, Petko M., Moser, Emily K., Tibbetts, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371696/
https://www.ncbi.nlm.nih.gov/pubmed/35921433
http://dx.doi.org/10.1073/pnas.2123362119