Low signaling efficiency from receptor to effector in olfactory transduction: A quantified ligand-triggered GPCR pathway

G protein–coupled receptor (GPCR) signaling is ubiquitous. As an archetype of this signaling motif, rod phototransduction has provided many fundamental, quantitative details, including a dogma that one active GPCR molecule activates a substantial number of downstream G protein/enzyme effector comple...

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Detalles Bibliográficos
Autores principales: Li, Rong-Chang, Molday, Laurie L., Lin, Chih-Chun, Ren, Xiaozhi, Fleischmann, Alexander, Molday, Robert S., Yau, King-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371729/
https://www.ncbi.nlm.nih.gov/pubmed/35914143
http://dx.doi.org/10.1073/pnas.2121225119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371729/
https://www.ncbi.nlm.nih.gov/pubmed/35914143
http://dx.doi.org/10.1073/pnas.2121225119

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