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Low signaling efficiency from receptor to effector in olfactory transduction: A quantified ligand-triggered GPCR pathway
G protein–coupled receptor (GPCR) signaling is ubiquitous. As an archetype of this signaling motif, rod phototransduction has provided many fundamental, quantitative details, including a dogma that one active GPCR molecule activates a substantial number of downstream G protein/enzyme effector comple...
Autores principales: | Li, Rong-Chang, Molday, Laurie L., Lin, Chih-Chun, Ren, Xiaozhi, Fleischmann, Alexander, Molday, Robert S., Yau, King-Wai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371729/ https://www.ncbi.nlm.nih.gov/pubmed/35914143 http://dx.doi.org/10.1073/pnas.2121225119 |
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