Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development

Cochlear hair cells (HCs) in the inner ear are responsible for sound detection. For HC fate specification, the master transcription factor Atoh1 is both necessary and sufficient. Atoh1 expression is dynamic and tightly regulated during development, but the cis-regulatory elements mediating this regu...

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Detalles Bibliográficos
Autores principales: Luo, Zhengnan, Du, Yi, Li, Shuting, Zhang, He, Shu, Muya, Zhang, Di, He, Shunji, Wang, Guangqin, Lu, Falong, Liu, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371730/
https://www.ncbi.nlm.nih.gov/pubmed/35925886
http://dx.doi.org/10.1073/pnas.2119850119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371730/
https://www.ncbi.nlm.nih.gov/pubmed/35925886
http://dx.doi.org/10.1073/pnas.2119850119

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