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Peptidoglycan-Mediated Bone Marrow Autonomic Neuropathy Impairs Hematopoietic Stem/Progenitor Cells via a NOD1-Dependent Pathway in db/db Mice

Impairment of bone marrow-derived hematopoietic stem/progenitor cells (HSPCs) contributes to the progression of vascular complications in subjects with diabetes. Very small amounts of bacterial-derived pathogen-associated molecular patterns (PAMPs) establish the bone marrow cell pool. We hypothesize...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Zhang, Binghan, Li, Shengbing, Chen, Wenwen, Mao, Jinning, Li, Ke, Liu, Dongfang, Duan, Yaqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371813/
https://www.ncbi.nlm.nih.gov/pubmed/35966130
http://dx.doi.org/10.1155/2022/4249843