mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation

mRNA 5′ cap recognition by eIF4F is a key element of eukaryotic translational control. Kinetic differences in eIF4F–mRNA interactions have long been proposed to mediate translation-efficiency differences between mRNAs, and recent transcriptome-wide studies have revealed significant heterogeneity in...

Descripción completa

Detalles Bibliográficos
Autores principales: Çetin, Burak, O’Leary, Seán E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371892/
https://www.ncbi.nlm.nih.gov/pubmed/35871304
http://dx.doi.org/10.1093/nar/gkac631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371892/
https://www.ncbi.nlm.nih.gov/pubmed/35871304
http://dx.doi.org/10.1093/nar/gkac631

Ejemplares similares