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mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation
mRNA 5′ cap recognition by eIF4F is a key element of eukaryotic translational control. Kinetic differences in eIF4F–mRNA interactions have long been proposed to mediate translation-efficiency differences between mRNAs, and recent transcriptome-wide studies have revealed significant heterogeneity in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371892/ https://www.ncbi.nlm.nih.gov/pubmed/35871304 http://dx.doi.org/10.1093/nar/gkac631 |