Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes

Gene expression is controlled in part by post-translational modifications of core histones. Methylation of lysine 4 of histone H3 (H3K4), associated with open chromatin and gene transcription, is catalyzed by type 2 lysine methyltransferase complexes that require WDR5, RBBP5, ASH2L and DPY30 as core...

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Detalles Bibliográficos
Autores principales: Bochyńska, Agnieszka, Stenzel, Alexander T, Sayadi Boroujeni, Roksaneh, Kuo, Chao-Chung, Barsoum, Mirna, Liang, Weili, Bussmann, Philip, Costa, Ivan G, Lüscher-Firzlaff, Juliane, Lüscher, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371893/
https://www.ncbi.nlm.nih.gov/pubmed/35819198
http://dx.doi.org/10.1093/nar/gkac591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371893/
https://www.ncbi.nlm.nih.gov/pubmed/35819198
http://dx.doi.org/10.1093/nar/gkac591

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