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Staphylococcal self-loading helicases couple the staircase mechanism with inter domain high flexibility

Replication is a crucial cellular process. Replicative helicases unwind DNA providing the template strand to the polymerase and promoting replication fork progression. Helicases are multi-domain proteins which use an ATPase domain to couple ATP hydrolysis with translocation, however the role that th...

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Detalles Bibliográficos
Autores principales: Qiao, Cuncun, Debiasi-Anders, Gianluca, Mir-Sanchis, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371898/
https://www.ncbi.nlm.nih.gov/pubmed/35871290
http://dx.doi.org/10.1093/nar/gkac625