Cooperative engagement and subsequent selective displacement of SR proteins define the pre-mRNA 3D structural scaffold for early spliceosome assembly

We recently reported that serine–arginine-rich (SR) protein-mediated pre-mRNA structural remodeling generates a pre-mRNA 3D structural scaffold that is stably recognized by the early spliceosomal components. However, the intermediate steps between the free pre-mRNA and the assembled early spliceosom...

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Detalles Bibliográficos
Autores principales: Saha, Kaushik, Ghosh, Gourisankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371905/
https://www.ncbi.nlm.nih.gov/pubmed/35871302
http://dx.doi.org/10.1093/nar/gkac636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371905/
https://www.ncbi.nlm.nih.gov/pubmed/35871302
http://dx.doi.org/10.1093/nar/gkac636

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