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SUPT3H-less SAGA coactivator can assemble and function without significantly perturbing RNA polymerase II transcription in mammalian cells

Coactivator complexes regulate chromatin accessibility and transcription. SAGA (Spt-Ada-Gcn5 Acetyltransferase) is an evolutionary conserved coactivator complex. The core module scaffolds the entire SAGA complex and adopts a histone octamer-like structure, which consists of six histone-fold domain (...

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Detalles Bibliográficos
Autores principales: Fischer, Veronique, Hisler, Vincent, Scheer, Elisabeth, Lata, Elisabeth, Morlet, Bastien, Plassard, Damien, Helmlinger, Dominique, Devys, Didier, Tora, László, Vincent, Stéphane D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371916/
https://www.ncbi.nlm.nih.gov/pubmed/35871303
http://dx.doi.org/10.1093/nar/gkac637