Spliceosomal SL1 RNA binding to U1-70K: the role of the extended RRM

The RNA recognition motif (RRM) occurs widely in RNA-binding proteins, but does not always by itself support full binding. For example, it is known that binding of SL1 RNA to the protein U1-70K in the U1 spliceosomal particle is reduced when a region flanking the RRM is truncated. How the RRM flanki...

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Detalles Bibliográficos
Autores principales: Gopan, Gopika, Ghaemi, Zhaleh, Davis, Caitlin M, Gruebele, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371917/
https://www.ncbi.nlm.nih.gov/pubmed/35876068
http://dx.doi.org/10.1093/nar/gkac599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371917/
https://www.ncbi.nlm.nih.gov/pubmed/35876068
http://dx.doi.org/10.1093/nar/gkac599

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