Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors

As part of our continuous studies on natural cholinesterase inhibitors from plant kingdom, the 95% ethanol extract from tubers of Bletilla striata showed promising butyrylcholinesterase (BChE) inhibition (IC(50) = 8.6 μg/mL). The extracts with different polarities (petroleum ether, ethyl acetate, n-...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Tu, Yanbei, Kang, Yunyao, Zhu, Chao, Wu, Chuanhai, Chen, Gang, Liu, Zerong, Li, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372051/
https://www.ncbi.nlm.nih.gov/pubmed/35953511
http://dx.doi.org/10.1038/s41598-022-17912-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372051/
https://www.ncbi.nlm.nih.gov/pubmed/35953511
http://dx.doi.org/10.1038/s41598-022-17912-7

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