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Machine learning-based protein crystal detection for monitoring of crystallization processes enabled with large-scale synthetic data sets of photorealistic images
Since preparative chromatography is a sustainability challenge due to large amounts of consumables used in downstream processing of biomolecules, protein crystallization offers a promising alternative as a purification method. While the limited crystallizability of proteins often restricts a broad a...
Autores principales: | Bischoff, Daniel, Walla, Brigitte, Weuster-Botz, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372129/ https://www.ncbi.nlm.nih.gov/pubmed/35661232 http://dx.doi.org/10.1007/s00216-022-04101-8 |
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