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PTEN inhibits AMPK to control collective migration

Pten is one of the most frequently mutated tumour suppressor gene in cancer. PTEN is generally altered in invasive cancers such as glioblastomas, but its function in collective cell migration and invasion is not fully characterised. Herein, we report that the loss of PTEN increases cell speed during...

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Detalles Bibliográficos
Autores principales: Peglion, Florent, Capuana, Lavinia, Perfettini, Isabelle, Boucontet, Laurent, Braithwaite, Ben, Colucci-Guyon, Emma, Quissac, Emie, Forsberg-Nilsson, Karin, Llense, Flora, Etienne-Manneville, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372137/
https://www.ncbi.nlm.nih.gov/pubmed/35953476
http://dx.doi.org/10.1038/s41467-022-31842-y