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MiRNA-494 specifically inhibits SIRT3-mediated microglia activation in sepsis-associated encephalopathy

BACKGROUND: Sepsis-associated encephalopathy (SAE) is characterized by the activation of inflammatory cascades, in which microglia play a key role. The activation of Recombinant Sirtuin 3 (SIRT3) was shown to significantly reduce the susceptibility of microglia to inflammatory stress. The purpose of...

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Detalles Bibliográficos
Autores principales: He, Chuanjiang, Aziguli, Abudureheman, Zhen, Jilun, Jiao, Ajin, Liao, Hongli, Du, Chunhui, Liu, Wen, Aihemaitijiang, Kaisaier, Xu, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372247/
https://www.ncbi.nlm.nih.gov/pubmed/35966295
http://dx.doi.org/10.21037/tcr-22-1732