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MiRNA-494 specifically inhibits SIRT3-mediated microglia activation in sepsis-associated encephalopathy
BACKGROUND: Sepsis-associated encephalopathy (SAE) is characterized by the activation of inflammatory cascades, in which microglia play a key role. The activation of Recombinant Sirtuin 3 (SIRT3) was shown to significantly reduce the susceptibility of microglia to inflammatory stress. The purpose of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372247/ https://www.ncbi.nlm.nih.gov/pubmed/35966295 http://dx.doi.org/10.21037/tcr-22-1732 |