Attenuation of HECT-E3 ligase expression rescued memory deficits in 3xTg-AD mice

Alzheimer's disease (AD) is one of the most common progressive neurodegenerative disorders that cause deterioration of cognitive functions. Recent studies suggested that the accumulation of inflammatory molecules and impaired protein degradation mechanisms might both play a critical role in the...

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Detalles Bibliográficos
Autores principales: Suresh, Pavithra, Jasmin, Sureka, Yen, Yun, Hsu, Hao-Jen, Varinthra, Peeraporn, Pairojana, Tanita, Chen, Chien-Chang, Liu, Ingrid Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372289/
https://www.ncbi.nlm.nih.gov/pubmed/35966798
http://dx.doi.org/10.3389/fnagi.2022.916904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372289/
https://www.ncbi.nlm.nih.gov/pubmed/35966798
http://dx.doi.org/10.3389/fnagi.2022.916904

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