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Attenuation of HECT-E3 ligase expression rescued memory deficits in 3xTg-AD mice
Alzheimer's disease (AD) is one of the most common progressive neurodegenerative disorders that cause deterioration of cognitive functions. Recent studies suggested that the accumulation of inflammatory molecules and impaired protein degradation mechanisms might both play a critical role in the...
Autores principales: | Suresh, Pavithra, Jasmin, Sureka, Yen, Yun, Hsu, Hao-Jen, Varinthra, Peeraporn, Pairojana, Tanita, Chen, Chien-Chang, Liu, Ingrid Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372289/ https://www.ncbi.nlm.nih.gov/pubmed/35966798 http://dx.doi.org/10.3389/fnagi.2022.916904 |
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