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Protease-activated receptor-2: Role in asthma pathogenesis and utility as a biomarker of disease severity

PAR(2), a receptor activated by serine proteases, has primarily pro-inflammatory roles in the airways and may play a role in asthma pathogenesis. PAR(2) exerts its effects in the lungs through activation of a variety of airway cells, but also activation of circulating immune cells. There is evidence...

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Detalles Bibliográficos
Autores principales: Gandhi, Vivek Dipak, Shrestha Palikhe, Nami, Vliagoftis, Harissios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372307/
https://www.ncbi.nlm.nih.gov/pubmed/35966869
http://dx.doi.org/10.3389/fmed.2022.954990