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Boosting the peripheral immune response in the skeletal muscles improved motor function in ALS transgenic mice

Monocyte chemoattractant protein-1 (MCP1) is one of the most powerful pro-inflammatory chemokines. However, its signaling is pivotal in driving injured axon and muscle regeneration. We previously reported that MCP1 is more strongly upregulated in the nervous system of slow-progressing than fast-prog...

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Detalles Bibliográficos
Autores principales: Trolese, Maria Chiara, Scarpa, Carlotta, Melfi, Valentina, Fabbrizio, Paola, Sironi, Francesca, Rossi, Martina, Bendotti, Caterina, Nardo, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372324/
https://www.ncbi.nlm.nih.gov/pubmed/35477657
http://dx.doi.org/10.1016/j.ymthe.2022.04.018