Snowflake: A deep learning-based human leukocyte antigen matching algorithm considering allele-specific surface accessibility

Histocompatibility in solid-organ transplantation has a strong impact on long-term graft survival. Although recent advances in matching of both B-cell epitopes and T-cell epitopes have improved understanding of allorecognition, the immunogenic determinants are still not fully understood. We hypothes...

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Detalles Bibliográficos
Autores principales: Niemann, Matthias, Matern, Benedict M., Spierings, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372366/
https://www.ncbi.nlm.nih.gov/pubmed/35967374
http://dx.doi.org/10.3389/fimmu.2022.937587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372366/
https://www.ncbi.nlm.nih.gov/pubmed/35967374
http://dx.doi.org/10.3389/fimmu.2022.937587

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