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Rechallenging Fluoropyrimidine-Induced Cardiotoxicity and Neurotoxicity: A Report of Two Cases

Fluoropyrimidines (FP’s) such as fluorouracil (5-FU) and capecitabine are antimetabolites widely used in many solid tumors. FPs side effects are caused mainly by a lack of dihydropyrimidine dehydrogenase (DPD) enzyme. It has been noticed that treatment with infusional regimens of 5-FU is associated...

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Detalles Bibliográficos
Autores principales: Ashish, Sethi, Raj, Moses S, Monga, Dulabh, Finley, Gene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372383/
https://www.ncbi.nlm.nih.gov/pubmed/35971344
http://dx.doi.org/10.7759/cureus.26824