p53 as a biomarker and potential target in gastrointestinal stromal tumors

KIT and PDGFRA play a major role in the oncogenic process in gastrointestinal stroma tumors (GIST) and small molecules have been employed with great success to target the KIT and PDGFRA pathways in this cancer. However, approximately 10% of patients with GIST are resistant to current targeted drug t...

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Detalles Bibliográficos
Autores principales: Wu, Chiao-En, Chen, Chiao-Ping, Huang, Wen-Kuan, Pan, Yi-Ru, Aptullahoglu, Erhan, Yeh, Chun-Nan, Lunec, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372431/
https://www.ncbi.nlm.nih.gov/pubmed/35965531
http://dx.doi.org/10.3389/fonc.2022.872202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372431/
https://www.ncbi.nlm.nih.gov/pubmed/35965531
http://dx.doi.org/10.3389/fonc.2022.872202

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