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T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition

During immune surveillance, CD8 T cells scan the surface of antigen-presenting cells using dynamic microvillar palpation and movements as well as by having their receptors preconcentrated into patches. Here, we use real-time lattice light-sheet microscopy to demonstrate the independence of microvill...

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Detalles Bibliográficos
Autores principales: Cai, En, Beppler, Casey, Eichorst, John, Marchuk, Kyle, Eastman, Scott W., Krummel, Matthew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372542/
https://www.ncbi.nlm.nih.gov/pubmed/35914144
http://dx.doi.org/10.1073/pnas.2203247119