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Is the Mutation Rate Lower in Genomic Regions of Stronger Selective Constraints?

A study of the plant Arabidopsis thaliana detected lower mutation rates in genomic regions where mutations are more likely to be deleterious, challenging the principle that mutagenesis is blind to its consequence. To examine the generality of this finding, we analyze large mutational data from baker...

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Detalles Bibliográficos
Autores principales: Liu, Haoxuan, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372563/
https://www.ncbi.nlm.nih.gov/pubmed/35907247
http://dx.doi.org/10.1093/molbev/msac169