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Is the Mutation Rate Lower in Genomic Regions of Stronger Selective Constraints?
A study of the plant Arabidopsis thaliana detected lower mutation rates in genomic regions where mutations are more likely to be deleterious, challenging the principle that mutagenesis is blind to its consequence. To examine the generality of this finding, we analyze large mutational data from baker...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372563/ https://www.ncbi.nlm.nih.gov/pubmed/35907247 http://dx.doi.org/10.1093/molbev/msac169 |