AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression

Macrophages play a major role in the immune defense against pathogenic factors; however, they can lead to tumor exacerbation and metastasis, as the tumor microenvironment (TME) polarizes tumor-associated macrophages (TAMs) into the M2 subtype. Lactate, a metabolite produced by carcinoma cells at hig...

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Detalles Bibliográficos
Autores principales: Shi, Yundi, Yasui, Masato, Hara-Chikuma, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372591/
https://www.ncbi.nlm.nih.gov/pubmed/35967760
http://dx.doi.org/10.1016/j.bbrep.2022.101317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372591/
https://www.ncbi.nlm.nih.gov/pubmed/35967760
http://dx.doi.org/10.1016/j.bbrep.2022.101317

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