Autoantibodies against NMDAR subunit NR1 disappear from blood upon anesthesia

Anesthetics penetrate the blood-brain-barrier (BBB) and - as confirmed preclinically – transiently disrupt it. An analogous consequence in humans has remained unproven. In mice, we previously reported that upon BBB dysfunction, the brain acts as ‘immunoprecipitator’ of autoantibodies against N-methy...

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Detalles Bibliográficos
Autores principales: Teller, Johannes, Jung, Carolin, Wilke, Justus B.H., Schimmelpfennig, Svea-Dorothée, Hindermann, Martin, Hinken, Lukas, Gabriel, Maria M., Fegbeutel, Christine, Schäfer, Andreas, Laser, Hans, Lichtinghagen, Ralf, Worthmann, Hans, Weissenborn, Karin, Ehrenreich, Hannelore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372600/
https://www.ncbi.nlm.nih.gov/pubmed/35965838
http://dx.doi.org/10.1016/j.bbih.2022.100494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372600/
https://www.ncbi.nlm.nih.gov/pubmed/35965838
http://dx.doi.org/10.1016/j.bbih.2022.100494

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