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An insight into the iPSCs-derived two-dimensional culture and three-dimensional organoid models for neurodegenerative disorders

The use of induced pluripotent stem cells (iPSCs) is a promising approach when used as models to study neurodegenerative disorders (NDDs) in vitro. iPSCs have been used in in vitro two-dimensional cultures; however, these two-dimensional cultures do not mimic the physiological three-dimensional cell...

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Detalles Bibliográficos
Autores principales: Bhargava, Anushka, Sandoval Castellanos, Ana M., Shah, Sonali, Ning, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372641/
https://www.ncbi.nlm.nih.gov/pubmed/35992771
http://dx.doi.org/10.1098/rsfs.2022.0040