Rhamnocitrin decreases fibrosis of ovarian granulosa cells by regulating the activation of the PPARγ/NF-κB/TGF-β1/Smad2/3 signaling pathway mediated by Wisp2

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in women. Rhamnocitrin (Rha) has anti-inflammatory and antioxidant actions. The WNT1-inducible-signaling pathway protein 2 (Wisp2) and nuclear factor (NF)-κB are involved in fibrosis in many diseases. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Yan-Yuan, He, Chun-Hua, Lan, Huan, Dong, Zhe-Wen, Wu, Ya-Qi, Song, Jia-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372664/
https://www.ncbi.nlm.nih.gov/pubmed/35965823
http://dx.doi.org/10.21037/atm-22-2496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372664/
https://www.ncbi.nlm.nih.gov/pubmed/35965823
http://dx.doi.org/10.21037/atm-22-2496

Ejemplares similares