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Rhamnocitrin decreases fibrosis of ovarian granulosa cells by regulating the activation of the PPARγ/NF-κB/TGF-β1/Smad2/3 signaling pathway mediated by Wisp2

BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in women. Rhamnocitrin (Rha) has anti-inflammatory and antioxidant actions. The WNT1-inducible-signaling pathway protein 2 (Wisp2) and nuclear factor (NF)-κB are involved in fibrosis in many diseases. We...

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Detalles Bibliográficos
Autores principales:	Zhou, Yan-Yuan, He, Chun-Hua, Lan, Huan, Dong, Zhe-Wen, Wu, Ya-Qi, Song, Jia-Le
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372664/ https://www.ncbi.nlm.nih.gov/pubmed/35965823 http://dx.doi.org/10.21037/atm-22-2496

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