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Interleukin-35 attenuates blood-brain barrier dysfunction caused by cerebral ischemia-reperfusion injury through inhibiting brain endothelial cell injury

BACKGROUND: Interleukin-35 (IL-35), an anti-inflammatory and antioxidant cytokine, plays a potent immunosuppressive role in various diseases. However, the effects of IL-35 on blood-brain barrier (BBB) dysfunction in ischemic stroke are not well characterized. METHODS: A total of 150 male C57BL/6 mic...

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Detalles Bibliográficos
Autores principales: Qian, Lei, Li, Ming, Lin, Xin, Teng, Hongwei, Yu, Lulu, Jiang, Maorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372693/
https://www.ncbi.nlm.nih.gov/pubmed/35965799
http://dx.doi.org/10.21037/atm-22-2770